Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults

Dear Study Team,

I am a patient in China and I am interested in participating in your clinical trial:

Study Title: Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults
ClinicalTrials.gov Identifier: NCT04608630
Sponsor: Australian and New Zealand Intensive Care Research Centre
Investigational product: Denosumab 60 MG/ML, Zoledronic Acid 5Mg/Bag 100Ml Inj, Sodium Chloride 0.9% or 5% Dextrose Intravenous, Sodium Chloride 0.9% Injection

About me:
- Age: (please fill in)
- Sex: (please fill in)
- Confirmed diagnosis and stage: (please fill in)
- Biomarkers / genetic testing: not available
- Prior and current treatments: (please fill in)
- Performance status (ECOG): not assessed
- Current location: China
- Travel ability: (please fill in)

Could you please let me know:
1. Whether I might be eligible for this study;
2. Which site would be closest and most practical for me, and whether remote pre-screening is possible;
3. What documents (medical records, pathology or imaging reports, recent labs) I should prepare for pre-screening.

I can provide English translations of my medical records. Thank you very much for your time and help.

Kind regards,
(your name)
(your email / phone with country code)

尊敬的研究团队：

我是一位来自中国的患者，希望咨询参加以下临床试验的可能：

研究名称：Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults
试验编号：NCT04608630
申办方：Australian and New Zealand Intensive Care Research Centre
研究药物：Denosumab 60 MG/ML、Zoledronic Acid 5Mg/Bag 100Ml Inj、Sodium Chloride 0.9% or 5% Dextrose Intravenous、Sodium Chloride 0.9% Injection

我的基本情况：
- 年龄：（请填写）
- 性别：（请填写）
- 确诊疾病与分期：（请填写）
- 基因／标志物检测：暂无
- 既往及当前治疗：（请填写）
- 体能状态（ECOG）：未评估
- 目前所在城市：中国
- 可前往范围：（请填写）

想请教三个问题：
1. 我是否可能符合本研究的入组标准？
2. 哪个中心对我最方便可行？能否远程预筛？
3. 预筛需要准备哪些资料（病历、病理、影像、近期化验）？

我可以提供英文翻译版病历。感谢您的时间与帮助。

顺祝安康
（您的姓名）
（您的邮箱／带国际区号的电话）