Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia
报名条件(概要)
- 年龄:18 Years – 不限
- 性别:不限
- 健康志愿者:不接受
完整入排标准请以官方页面为准。
开展国家/地区
United States
药品与企业信息
其他名称:2-(1,2-dihydroxyethyl)-4,5-dihydroxy-furan-3-one、Asorbicap、C Vitamin、C-Long、Ce-Vi-Sol、Cecon
Given IV
其他名称:Blastocarb、Carboplat、Carboplatin Hexal、Carboplatino、Carboplatinum、Carbosin
Given IV or PO
其他名称:Abiplatin、Blastolem、Briplatin、CDDP、Cis-diammine-dichloroplatinum、Cis-diamminedichloridoplatinum
Given IV or PO
其他名称:.beta.-Cytosine arabinoside、1-.beta.-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone、1-.beta.-D-Arabinofuranosylcytosine、1-Beta-D-arabinofuranosyl-4-amino-2(1H)pyrimidinone、1-Beta-D-arabinofuranosylcytosine、1.beta.-D-Arabinofuranosylcytosine
Given IV or PO
其他名称:Demethyl Epipodophyllotoxin Ethylidine Glucoside、EPEG、Lastet、Toposar、Vepesid、VP 16
Given IV or PO
其他名称:dFdCyd、Difluorodeoxycytidine Hydrochloride、Gemcitabine HCI、Gemzar、LY-188011、LY188011
Given IV or PO
研发企业
试验官方登记的主要申办方;研究机构申办时会显示相应机构名称。
生产企业
Cisplatin
WG Critical Care, LLC
合作机构
- National Cancer Institute (NCI)美国国立卫生研究院
研发企业与生产企业可能不是同一家。研究阶段药品可能尚未公布生产企业;生产企业仅取自美国上市原研药说明书所列企业(不含仿制药),不作推测;仅在其他国家上市的药品暂无法显示。
研究简介(原文)
This phase II trial studies the effect of ascorbic acid and combination chemotherapy in treating patients with lymphoma that has come back (recurrent) or does not respond to therapy (refractory), clonal cytopenia of undetermined significance and chronic myelomonocytic leukemia (CMML). Ascorbic acid may make cancer cells more sensitive to chemotherapy. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ascorbic acid and combination chemotherapy may kill more cancer cells. Arms A, B, C, and D are closed to enrollment.
适应症
主动联系研究团队
这项试验目前在中国大陆没有研究中心
这种情况下,直接发"入组咨询"往往会被回复"您所在地区没有中心"。更有效的做法是申请同情用药/扩展准入(由主治医生一同提出),或询问能否到最近的境外中心参加。下面已为您切换到对应的信件版本。
查看完整申请路径与成功率说明 →总联系人(申办方/研究总部)
- Clinical Trials Referral Officemayocliniccancerstudies@mayo.edu855-776-0015
研究中心联系方式
- Mayo Clinic Health Systems-MankatoMankato,Minnesota,United States
- Mayo Clinic in RochesterRochester,Minnesota,United States
- Mayo Clinic Health System-Eau Claire ClinicEau Claire,Wisconsin,United States
问自己是否符合条件、如何预筛
我的病情档案
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英文版(发给研究团队)
Dear Study Team, I am a patient in China and I am interested in participating in your clinical trial: Study Title: Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia ClinicalTrials.gov Identifier: NCT03418038 Sponsor: Mayo Clinic Investigational product: Ascorbic Acid, Carboplatin, Cisplatin, Cytarabine, Dexamethasone About me: - Age: (please fill in) - Sex: (please fill in) - Confirmed diagnosis and stage: (please fill in) - Biomarkers / genetic testing: not available - Prior and current treatments: (please fill in) - Performance status (ECOG): not assessed - Current location: China - Travel ability: (please fill in) Could you please let me know: 1. Whether I might be eligible for this study; 2. Which site would be closest and most practical for me, and whether remote pre-screening is possible; 3. What documents (medical records, pathology or imaging reports, recent labs) I should prepare for pre-screening. I can provide English translations of my medical records. Thank you very much for your time and help. Kind regards, (your name) (your email / phone with country code)
中文对照(供您核对)
尊敬的研究团队: 我是一位来自中国的患者,希望咨询参加以下临床试验的可能: 研究名称:Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia 试验编号:NCT03418038 申办方:Mayo Clinic 研究药物:Ascorbic Acid、Carboplatin、Cisplatin、Cytarabine、Dexamethasone 我的基本情况: - 年龄:(请填写) - 性别:(请填写) - 确诊疾病与分期:(请填写) - 基因/标志物检测:暂无 - 既往及当前治疗:(请填写) - 体能状态(ECOG):未评估 - 目前所在城市:中国 - 可前往范围:(请填写) 想请教三个问题: 1. 我是否可能符合本研究的入组标准? 2. 哪个中心对我最方便可行?能否远程预筛? 3. 预筛需要准备哪些资料(病历、病理、影像、近期化验)? 我可以提供英文翻译版病历。感谢您的时间与帮助。 顺祝安康 (您的姓名) (您的邮箱/带国际区号的电话)
提示:请与主治医生一起发信——由医生署名的申请,回复率远高于患者单独发信。首封邮件不要附身份证号等敏感信息。研究团队通常在 3–10 个工作日内回复,两周无回音可礼貌追问一次。
下一步怎么做?
- 把本页信息带给您的主治医生,评估是否适合参加。
- 点击下方按钮打开官方注册页,查看研究中心联系方式。
- 直接联系研究团队咨询报名事宜(通常有中文同声翻译服务可协助沟通)。