imatinib
imatinib 是目前在国外临床研究中出现的一款新药或疗法,主要研究方向为Inherited Bone Marrow Failure Syndrome、Familial Platelet Disorder With Predisposition to Myeloid Malignancies。下面汇总了它当前在全球正在招募患者的研究,以及中国患者可以走的申请途径。
24 项
全球在招研究
2 项
已进入 III/IV 期
26 个
开展国家和地区
有
中国境内设点
药品与企业信息
研发企业
- National Cancer Institute (NCI)
- Kumquat Biosciences Inc.
- GlaxoSmithKline
- Novartis Pharmaceuticals
- Vastra Gotaland Region
- Wei Zhao
- University of California, San Francisco
- Hikma Pharmaceuticals LLC
汇总自相关试验登记的主要申办方;研究机构申办时会显示相应机构名称。
生产企业
公开药品批准资料或正式说明书暂未提供明确的生产企业信息。
研发企业与生产企业可能不是同一家。研究阶段药品可能尚未公布生产企业;生产企业仅取自美国上市原研药说明书所列企业(不含仿制药),不作推测;仅在其他国家上市的药品暂无法显示。
主要开展国家和地区
美国、Argentina、澳大利亚、Brazil、加拿大、中国、芬兰、法国、Greece、意大利、日本、荷兰
正在招募患者的 imatinib 研究
Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency
I 期招募中美国NCT06090669KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)
II 期招募中美国NCT07406633A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline)
III 期招募中美国Argentina澳大利亚BrazilNCT07585266A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) Therapy
不适用招募中美国NCT07091019Use of Imatinib to Convert Triple Negative Breast Cancer Into ER-positive Breast Cancer (I-CONIC)
不适用招募中瑞典NCT05722795Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic Disease
IV 期招募中中国NCT03844360A Study on the Tolerability, Safety and Effectiveness of Asciminib in Patients With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in the Chronic Phase in Germany
不适用招募中德国NCT07549516Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma
II 期招募中美国NCT04598009Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia
不适用招募中EgyptNCT05282108Long-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational Study
不适用招募中荷兰NCT075227625 Years of Adjuvant Imatinib in Patients With Gastrointestinal Stromal Tumor With a High Risk
II 期招募中South KoreaNCT05385549A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
II 期招募中美国澳大利亚加拿大Puerto RicoNCT06124157Lenvatinib After Progression on Imatinib, Sunitinib, and Regorafenib for GIST Patients
I 期 / II 期招募中South KoreaNCT07096609A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
II 期招募中美国比利时德国意大利NCT07124078Chart Review Study of Chronic Myelogenous Leukemia (CML) Patients Treated With Imatinib Outside of a Clinical Trial
不适用招募中美国NCT00816114Randomized Trial in Adult de Novo Ph Positive ALL With Chemotherapy, Imatinib or Ponatinib, Blinatumomab and SCT
II 期招募中德国NCT06061094Imatinib and Trametinib for KRAS-mutated Solid Tumor
I 期招募中中国台湾NCT06962254A Study of Velzatinib in Participants With Metastatic and/or Unresectable GIST After Imatinib, Sunitinib, Regorafenib, and Pimitespib
II 期招募中日本NCT07689201Safety and Efficacy of Imatinib in Combination With Artemether-Lumefantrine for Uncomplicated Malaria
II 期招募中KenyaNCT07559370COMPERA / COMPERA-KIDS
不适用招募中比利时德国意大利瑞士NCT01347216Ponatinib Hydrochloride as Second Line Therapy in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase Resistant or Intolerant to Imatinib Mesylate, Dasatinib, or Nilotinib
II 期招募中美国NCT01746836Precision Cancer Therapy in Rare Cancers
II 期招募中挪威NCT06119789Ma-Spore ALL 2020 Study
II 期招募中MalaysiaSingaporeNCT06336395A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
I 期招募中美国NCT06655246
中国患者怎么争取用上这款药
这款药已经有研究在中国境内设点,可以先带完整病历去对应医院咨询入组;同时也可以并行了解下面几条途径,多一条备选。
查看完整申请指南本页信息整理自 ClinicalTrials.gov 公开登记数据,仅供参考,不构成医疗建议;是否适合使用该药物,请以专业医生和研究团队的意见为准。