Pembrolizumab
Pembrolizumab 是目前在国外临床研究中出现的一款新药或疗法,主要研究方向为Metastatic Non-small Cell Lung Cancer With MTAP Deletion、Non-small Cell Lung Cancer、Carcinoma, Non-Small-Cell Lung、Metastatic Colorectal Cancer。下面汇总了它当前在全球正在招募患者的研究,以及中国患者可以走的申请途径。
24 项
全球在招研究
2 项
已进入 III/IV 期
18 个
开展国家和地区
有
中国境内设点
药品与企业信息
研发企业
- Bristol-Myers Squibb
- Mirati Therapeutics Inc.
- National Cancer Institute (NCI)
- Alentis Therapeutics AG
- AbbVie
- VM Oncology, LLC
- Merck Sharp & Dohme LLC
- Fudan University
汇总自相关试验登记的主要申办方;研究机构申办时会显示相应机构名称。
生产企业
公开药品批准资料或正式说明书暂未提供明确的生产企业信息。
研发企业与生产企业可能不是同一家。研究阶段药品可能尚未公布生产企业;生产企业仅取自美国上市原研药说明书所列企业(不含仿制药),不作推测;仅在其他国家上市的药品暂无法显示。
主要开展国家和地区
美国、Puerto Rico、Brazil、Chile、中国、Czechia、法国、德国、意大利、日本、挪威、Singapore
正在招募患者的 Pembrolizumab 研究
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
I 期 / II 期招募中美国Puerto RicoNCT03556228Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)
I 期 / II 期招募中美国BrazilChile中国NCT06780111Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
II 期招募中中国NCT06121700A Clinical Trial Evaluating TQB2102 for Injection in Combination With Behmosubaisumab/Payamprolizumab With or Without Chemotherapy in Unresectable Locally Advanced, Recurrent, or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastroesophageal Adenocarcinoma
II 期招募中中国NCT06767800Pembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma
II 期招募中SingaporeNCT06160843Histotripsy in Biliary Tract Cancer
不适用招募中美国NCT07853690A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs)
II 期招募中美国NCT07743190A Personalized Neoantigen Cancer Vaccine in Treatment Naïve, Asymptomatic Patients With IGHV Unmutated CLL.
I 期招募中美国NCT03219450PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC
II 期招募中美国NCT06245889Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers
早期 I 期招募中美国NCT05553782Viscum Album for TNBC on Adjuvant Pembrolizumab
IV 期招募中South KoreaNCT06920810Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC
II 期招募中美国NCT06745882Effect of Postbiotics on Microbiota and Systemic Immunomodulation of Pembrolizumab as First-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (RM HNSCC)
II 期招募中意大利NCT07485296Pembrolizumab, Ibrutinib and Rituximab in PCNSL
I 期 / II 期招募中美国NCT04421560A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
I 期 / II 期招募中美国中国法国德国NCT06385080Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers
III 期招募中法国NCT04747054Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology
II 期招募中美国NCT05756569I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
II 期招募中美国NCT01042379Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma
I 期招募中美国NCT05603910A Study of SKB571 Combination Therapy in Participants With Non-Small Cell Lung Cancer (NSCLC)
II 期招募中中国NCT07622186A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
II 期招募中美国NCT02621021A Study of BL-B01D1 + Pembrolizumab ± Bevacizumab in Patients With Recurrent or Metastatic Cervical Cancer and Endometrial Cancer
II 期招募中中国NCT07054567Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer
I 期 / II 期招募中South KoreaNCT04592211Capecitabine Plus Pembrolizumab in Patients With Triple Negative Breast Cancer After Chemo-immunotherapy and Surgery
II 期招募中法国NCT05973864
中国患者怎么争取用上这款药
这款药已经有研究在中国境内设点,可以先带完整病历去对应医院咨询入组;同时也可以并行了解下面几条途径,多一条备选。
查看完整申请指南同类方向的其他在研新药
本页信息整理自 ClinicalTrials.gov 公开登记数据,仅供参考,不构成医疗建议;是否适合使用该药物,请以专业医生和研究团队的意见为准。