Sildenafil
Sildenafil 是目前在国外临床研究中出现的一款新药或疗法，主要研究方向为Scleroderma、Mildly Elevated Pulmonary Pressures。下面汇总了它当前在全球正在招募患者的研究，以及中国患者可以走的申请途径。
21 项
全球在招研究
7 项
已进入 III/IV 期
21 个
开展国家和地区
有
中国境内设点
药品与企业信息
研发企业
- Johns Hopkins University
- Mansoura University
- University of Sao Paulo General Hospital
- University of Alberta
- Chinese University of Hong Kong
- University Hospital, Rouen
- Silvia Ulrich
- Ryan Flannigan, MD
汇总自相关试验登记的主要申办方；研究机构申办时会显示相应机构名称。
生产企业
公开药品批准资料或正式说明书暂未提供明确的生产企业信息。
研发企业与生产企业可能不是同一家。研究阶段药品可能尚未公布生产企业；生产企业仅取自美国上市原研药说明书所列企业（不含仿制药），不作推测；仅在其他国家上市的药品暂无法显示。
主要开展国家和地区
Egypt、Brazil、加拿大、中国香港、法国、瑞士、美国、比利时、德国、意大利、荷兰、Argentina
正在招募患者的 Sildenafil 研究
Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients
IV 期招募中EgyptNCT07391579Randomized Study of Triple Therapy vs Sildenafil Dose Optimization in Pulmonary Arterial Hypertension
IV 期招募中BrazilNCT07713914Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD
II 期招募中加拿大NCT05061368Switching of Sildenafil to Riociguat in CTEPH Patients
IV 期招募中中国香港NCT06715280Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer
III 期招募中法国NCT06123156The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension
II 期 / III 期招募中瑞士NCT07824674A Single-Arm, Dose Escalation of an Intraurethral Alprostadil Paste for Erectile Dysfunction
II 期招募中加拿大NCT07601646Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis
II 期招募中法国瑞士NCT06954597Sildenafil for Microvasculopathy in Chronic TBI
II 期招募中美国NCT05782244Sildenafil for Early Pulmonary Vascular Disease in Scleroderma
II 期招募中美国NCT04797286Metabolomics of Cancers of the Upper Aerodigestive Tract
不适用招募中法国NCT07377084COMPERA / COMPERA-KIDS
不适用招募中比利时德国意大利瑞士NCT01347216A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)
II 期招募中美国NCT05201144Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn
I 期 / II 期招募中EgyptNCT04898114PEnile ReHABilitation After Nerve Sparing Robot-assisted Radical Prostatectomy for Prostate Cancer 2.0 (PEHAB-II)
IV 期招募中荷兰NCT06875258Sildenafil to Reduce Vascular Remodeling During Left Ventricular Assist Device Support
早期 I 期招募中美国NCT06510322IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver Disease
I 期招募中美国NCT06324396Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients
IV 期招募中Argentina奥地利Czechia法国NCT06317805The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fed Versus 100 mg of Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fasted Conditions in Healthy Adult Male Subjects
I 期招募中美国NCT06872866Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth Asphyxia
II 期招募中美国加拿大NCT06098833Efficacy and Safety of Triple-targeted Drug Therapy in Treatment-naive Patients With Non-low-risk PAH: A Real-world, Multicenter Study
不适用招募中中国NCT06753981
中国患者怎么争取用上这款药
这款药已经有研究在中国境内设点，可以先带完整病历去对应医院咨询入组；同时也可以并行了解下面几条途径，多一条备选。
查看完整申请指南同类方向的其他在研新药
本页信息整理自 ClinicalTrials.gov 公开登记数据，仅供参考，不构成医疗建议；是否适合使用该药物，请以专业医生和研究团队的意见为准。