Vonoprazan
Vonoprazan 是目前在国外临床研究中出现的一款新药或疗法，主要研究方向为Erosive Esophagitis、Heartburn、Symptomatic Non-erosive Gastroesophageal Reflux Disease、Helicobacter Pylori Infection。下面汇总了它当前在全球正在招募患者的研究，以及中国患者可以走的申请途径。
24 项
全球在招研究
12 项
已进入 III/IV 期
6 个
开展国家和地区
有
中国境内设点
药品与企业信息
研发企业
- Phathom Pharmaceuticals, Inc.
- Tanta University
- The First Affiliated Hospital with Nanjing Medical University
- Kaohsiung Medical University
- Asian Institute of Gastroenterology, India
- First Affiliated Hospital of Chongqing Medical University
- Dow University of Health Sciences
- Nanjing First Hospital, Nanjing Medical University
汇总自相关试验登记的主要申办方；研究机构申办时会显示相应机构名称。
生产企业
公开药品批准资料或正式说明书暂未提供明确的生产企业信息。
研发企业与生产企业可能不是同一家。研究阶段药品可能尚未公布生产企业；生产企业仅取自美国上市原研药说明书所列企业（不含仿制药），不作推测；仅在其他国家上市的药品暂无法显示。
主要开展国家和地区
Egypt、中国、中国台湾、India、Pakistan、美国
正在招募患者的 Vonoprazan 研究
Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection
III 期招募中EgyptNCT07275827VA Dual Sequential Therapy
IV 期招募中中国NCT06929962Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication
不适用招募中中国台湾NCT06349486A Randomized, Three-Arm Study Comparing Vonaprazan 10 mg, Vonaprazan 20 mg, and Esomeprazole 40 mg for the Healing of LA Grade B or Higher Reflux Esophagitis at 8 Weeks
不适用招募中IndiaNCT06953986The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant Recipients
I 期 / II 期招募中中国NCT07275632CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Eradication
IV 期招募中PakistanNCT07344506Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection
II 期招募中EgyptNCT07293910Eradication of Helicobacter Pylori Improves Metabolic Syndrome Through Modulation of Gut Microbiota.
IV 期招募中中国NCT07306988Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication
不适用招募中中国NCT07439445Evaluating the Efficacy of Vonoprazan in Preventing Post-Endoscopic Variceal Band Ligation Ulcers: A Randomized Controlled Trial
II 期招募中PakistanNCT07267260Vonaprazan Versus Esomeprazole for Healing of LA Grade B or Higher Esophagitis After POEM
不适用招募中IndiaNCT06955520P-CABs-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication
不适用招募中中国NCT07285096A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
不适用招募中美国NCT06660342Vonoprazan Evaluation Compared to Standard Triple Therapy in Helicobacter Pylori eRadication
IV 期招募中IndiaNCT06959368Vonoprazan Alone vs With Itopride for Functional Dyspepsia: The VIVA Trial
不适用招募中IndiaNCT07731542PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers
IV 期招募中中国NCT05582174Efficacy of Vonoprazan Based Dual and Triple Therapy for Patient With Helicobacter Pylori Infection
不适用招募中EgyptNCT070456887-Day Vonoprazan, High-Dose Amoxicillin, and Bismuth Therapy
IV 期招募中中国NCT07232095Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor as A Part of Bismuth Based Quadruple Therapy for Treatment of Helicobacter Pylori Infection
不适用招募中EgyptNCT07165444The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients
IV 期招募中中国NCT04728516Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradication: A Prospective, Randomized Controlled Clinical Trial
IV 期招募中中国NCT07068607Head-to-head Study of Tegoprazan 50 mg BID Plus Amoxicillin 1 g TID vs. Vonoprazan 20 mg BID Plus Amoxicillin 1 g TID for H. Pylori Eradication
II 期 / III 期招募中中国NCT07242456Clinical Study Evaluating The Role of Vonoprazan Versus Pantoprazole in Patients With Gastroesophageal Reflux Disease
IV 期招募中EgyptNCT06564246Effect of Bismuth Add-on to Dual Therapy for Helicobacter Pylori Eradication
III 期招募中中国台湾NCT07576959
中国患者怎么争取用上这款药
这款药已经有研究在中国境内设点，可以先带完整病历去对应医院咨询入组；同时也可以并行了解下面几条途径，多一条备选。
查看完整申请指南同类方向的其他在研新药
本页信息整理自 ClinicalTrials.gov 公开登记数据，仅供参考，不构成医疗建议；是否适合使用该药物，请以专业医生和研究团队的意见为准。