Letrozole
Letrozole 是目前在国外临床研究中出现的一款新药或疗法,主要研究方向为Advanced Solid Tumor、HR+/HER2- Breast Cancer、HR+, HER2-, Advanced Breast Cancer、CCNE1 Amplification。下面汇总了它当前在全球正在招募患者的研究,以及中国患者可以走的申请途径。
24 项
全球在招研究
8 项
已进入 III/IV 期
31 个
开展国家和地区
有
中国境内设点
药品与企业信息
研发企业
- Avenzo Therapeutics, Inc.
- Novartis Pharmaceuticals
- The University of Hong Kong
- Mỹ Đức Hospital
- University of Texas Southwestern Medical Center
- QuantumLeap Healthcare Collaborative
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
- Celcuity Inc
汇总自相关试验登记的主要申办方;研究机构申办时会显示相应机构名称。
生产企业
公开药品批准资料或正式说明书暂未提供明确的生产企业信息。
研发企业与生产企业可能不是同一家。研究阶段药品可能尚未公布生产企业;生产企业仅取自美国上市原研药说明书所列企业(不含仿制药),不作推测;仅在其他国家上市的药品暂无法显示。
主要开展国家和地区
中国香港、Vietnam、美国、加拿大、Czechia、丹麦、法国、德国、意大利、日本、Singapore、西班牙
正在招募患者的 Letrozole 研究
Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy
不适用招募中中国香港NCT05487092Artificial Cycle With or Without GnRH Agonist Pre-treatment for Frozen Embryo Transfer in Adenomyosis Patients
不适用招募中VietnamNCT06239376Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
I 期 / II 期招募中美国加拿大Czechia丹麦NCT07288359Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib
II 期招募中美国NCT04614194I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
II 期招募中美国NCT01042379Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism
不适用招募中EgyptNCT06041204Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
III 期招募中美国Argentina澳大利亚比利时NCT06757634SNF Platform Study of HR+/ HER2-advanced Breast Cancer
II 期招募中中国NCT05594095Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial)
III 期招募中意大利NCT05601700Phase II/III Study of SPH4336 Combined With Letrozole vs Placebo Combined With Letrozole in First-line Treatment of Breast Cancer
II 期 / III 期招募中中国NCT05744687Entinostat Plus Pyrotinib and Endocrine Therapy in Advanced Triple-Positive Breast Cancer After Trastuzumab Failure
I 期 / II 期招募中中国NCT07708194Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS
不适用招募中BangladeshNCT07255911Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
II 期招募中美国NCT05472792A Study of GB491 in Combination With Letrozole in Patients With HR Positive and HER2 Negative Advanced Breast Cancer
III 期招募中中国NCT05851014Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed Miscarriage
IV 期招募中PakistanNCT07160855Trastuzumab Deruxtecan Versus Standard Neoadjuvant Treatment for HER2-positive Breast Cancer
II 期招募中瑞典NCT05900206Iparomlimab and Tuvonralimab (QL1706) in Patients With HR-positive, HER2-negative Advanced Breast Cancer
II 期招募中中国NCT07180160A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
II 期招募中美国ArgentinaBrazil加拿大NCT07054190Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)
III 期招募中比利时Cyprus法国德国NCT05512364Combination of Abemaciclib and Endocrine Therapy in Hormone Receptor Positive HER2 Negative Locally Advanced or Metastatic Breast Cancer With Focus on Digital Side Effect Management
IV 期招募中德国瑞士NCT05362760A Trial of HRS-6209 in Combination With Other Antitumor Therapies in Breast Cancer Patients or HRS-9813 as Monotherapy in Patients With Advanced Solid Tumors
I 期 / II 期招募中中国NCT06555068Pyrotinib Maleate, Trastuzumab, SHR6390 and Letrozole in Combination for Stage II-III TPBC
II 期招募中中国NCT05228951First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
I 期 / II 期招募中美国比利时法国德国NCT05768139De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
III 期招募中美国加拿大中国香港日本NCT04852887
中国患者怎么争取用上这款药
这款药已经有研究在中国境内设点,可以先带完整病历去对应医院咨询入组;同时也可以并行了解下面几条途径,多一条备选。
查看完整申请指南同类方向的其他在研新药
本页信息整理自 ClinicalTrials.gov 公开登记数据,仅供参考,不构成医疗建议;是否适合使用该药物,请以专业医生和研究团队的意见为准。