Methotrexate
Methotrexate 是目前在国外临床研究中出现的一款新药或疗法，主要研究方向为Acute Lymphoblastic Leukemia。下面汇总了它当前在全球正在招募患者的研究，以及中国患者可以走的申请途径。
24 项
全球在招研究
7 项
已进入 III/IV 期
24 个
开展国家和地区
有
中国境内设点
药品与企业信息
研发企业
- Northside Hospital, Inc.
- Children's Oncology Group
- Cincinnati Eye Institute, Southwest Ohio
- Lahore General Hospital
- Assistance Publique - Hôpitaux de Paris
- Amgen
- Swiss Dermatology Network for Targeted Therapies
- Andrew E. Place, MD
汇总自相关试验登记的主要申办方；研究机构申办时会显示相应机构名称。
生产企业
- Hospira, Inc.
研发企业与生产企业可能不是同一家。研究阶段药品可能尚未公布生产企业；生产企业仅取自美国上市原研药说明书所列企业（不含仿制药），不作推测；仅在其他国家上市的药品暂无法显示。
主要开展国家和地区
美国、澳大利亚、加拿大、新西兰、Puerto Rico、Pakistan、法国、瑞士、德国、Bangladesh、中国、Egypt
正在招募患者的 Methotrexate 研究
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
III 期招募中美国澳大利亚加拿大新西兰NCT03959085Prevention of ProliFerative Vitreoretinopathy With Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial
II 期招募中美国NCT06541574Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque Psoriasis
早期 I 期招募中PakistanNCT07261306Baricitinib in Patients With Relapsing or naïve Dermatomyositis
III 期招募中法国NCT04972760A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
III 期招募中美国Puerto RicoNCT07388498Swiss Dermatology Network of Targeted Therapies (SDNTT)
不适用招募中瑞士NCT01706692Venetoclax Basket Trial for High Risk Hematologic Malignancies
I 期招募中美国NCT05292664Evaluation of Acute and Chronic Nephrotoxicity in Acute Lymphatic Leukemia Patients Using Ultrasound Localization Microscopy
不适用招募中德国NCT07313878Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate
III 期招募中BangladeshNCT06936215Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule
不适用招募中中国NCT03785574Effect of Diosmin and Hesperidin in Treatment of Patients With Rheumatoid Arthritis
III 期招募中EgyptNCT05756179Exploration of the Application of Methotrexate-loaded Drug Vesicles in Intrathecal Injection for Meningeal Metastasis of Lung Cancer
I 期 / II 期招募中中国NCT07559097Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
早期 I 期招募中美国澳大利亚加拿大德国NCT06333899Lenalidomide Maintenance Treatment in Patients With Primary Central Nervous System Lymphoma
II 期招募中South KoreaNCT05260619Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia
II 期招募中中国NCT06816134Clinical Efficacy of Telitacicept in Sjögren's Disease With Interstitial Lung Disease
不适用招募中中国NCT07843381Evolution of Intestinal Microbiota in Patients With Juvenile Spondylarthropathy According to Typology of Treatment
不适用招募中法国NCT04540432Zanubrutinib in Combination With Pola-R-CHP and High-dose Methotrexate in Patients With Secondary CNS Lymphoma
I 期招募中美国NCT06730542ZR-MTX for PIOL Phase II Trial
II 期招募中中国NCT06973811Influence of Methotrexate Discontinuation on Immunogenicity After PCV-20 Vaccine in Patients ARDs
IV 期招募中BrazilNCT07242092SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
不适用招募中荷兰NCT07021495HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies
I 期 / II 期招募中奥地利比利时丹麦芬兰NCT05658640The Clinical Efficacy of Immunomodulators in RA Patients
IV 期招募中中国NCT05626348Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis
不适用招募中中国NCT06301373
中国患者怎么争取用上这款药
这款药已经有研究在中国境内设点，可以先带完整病历去对应医院咨询入组；同时也可以并行了解下面几条途径，多一条备选。
查看完整申请指南同类方向的其他在研新药
本页信息整理自 ClinicalTrials.gov 公开登记数据，仅供参考，不构成医疗建议；是否适合使用该药物，请以专业医生和研究团队的意见为准。